University Hospital Bonn Lead institution 1 results Added 2 August 2021 Onchocerciasis LAMP assay to optimize diagnostics and sampling strategies for low-prevalence settings in Cameroon University Hospital Bonn Research question 1. Can the O-150 LAMP assay be established on whole blood? 2. Can the O-150 qPCR methodology be adapted for human sampling? Secondary 1. How does the performance of the O-150 LAMP compare to the O-150 qPCR assay? 2. What threshold be used to define positive vs negative results for both assays? 3. Can deep sequencing reveal over potential biomarkers for further investigation?