Celebrating World NTD Day and Other NTD News

This news roundup is a collection of headlines and other items on neglected tropical diseases, and does not reflect the work or the views of the Coalition for Operational Research on Neglected Tropical Diseases or the Neglected Tropical Diseases Support Center.

Photo credit: Louise Gubb/RTI Fights NTDs

 

Lymphatic filariasis

Lymphatic filariasis elimination status: Wuchereria bancrofti infections ...

Eliza T. Lupenza, Dinah B. Gasarasi and Omary M. Minzi, PLOS One

There is a significant decline in LF transmission in Masasi District after seven rounds of MDA. However, the presence of individuals who are persistently non-compliant may delay elimination of LF in the District.

Mass spectrometric and glycan microarray-based characterization ...

Laudine M.C.Petralia et al., Molecular & Cellular Proteomics

Altogether, our work identifies B. malayi N-linked and GSL-glycan antigens and reveals antibody responses from the host that could be exploited as potential markers for LF.

Pharmacological Treatment of Secondary Lymphedema

Stav Brown et al., Frontiers in Pharmacology

The purpose of this review is to summarize current experimental pharmacological strategies in the treatment of lymphedema.

Onchocerciasis

Reducing onchocerciasis-associated morbidity in onchocerciasis-endemic foci ...

Robert Colebunders et al., International Journal of Infectious Diseases

We argue that clinical trials are needed to investigate the safety and efficacy of ivermectin treatment of Onchocerca volvulus-infected pregnant women and of children aged <5 years. Crucially, six-monthly administration of ivermectin in school-age children at risk of onchocerciasis-associated-epilepsy could be achieved by supplementing annual CDTI with an extra round of ivermectin treatment during Child Health Days in schools and/or other distribution sites every year. 

Reaching the Last Mile: The Trachoma Investigators of Mozambique

RTI

They discovered that some communities were even more isolated and remote than anticipated. Supervisors, who play a key role in ensuring the quality and effectiveness of treatment campaigns, were struggling to reach these communities due to intense logistical obstacles. They also found that access to safe and clean water, sanitation and hygiene services were limited in many of these communities. Once the investigation was complete, the team worked to rapidly respond to findings in time for the next round of treatment, which was scheduled a couple of months later.

Schistosomiasis

Schistosomiasis, soil transmitted helminthiasis, and malaria co-infections ...

Victor Tunje Jeza et al., BMC Public Health

The use of improved WASH activities might have contributed to the low prevalence of STHs and S. haematobium infections. Further, bed net ownership and usage might have resulted in the low prevalence of Plasmodium sp. infections observed.

Schistosomiasis in Gabon from 2000 to 2021 - A review

Jean ClaudeDejon-Agobé et al., Acta Tropica

Progress has been made over the past two decades in the understanding of schistosomiasis in the country, including disease-related morbidity and its interaction with other parasitic infections, and the immunology and epidemiology of the disease. However, for optimising control of the disease, there is a need to fine-tune these findings with detailed local epidemiological and malacological data.

Merck KGaA, Darmstadt, Germany, Provides 1.5 Billionth Tablet of Praziquantel ...

Timo Breiner, Merck KGaA

Merck KGaA, Darmstadt, Germany, a leading science and technology company, has donated the 1.5 billionth tablet of praziquantel in partnership with the World Health Organization (WHO). 

Efficacy of Praziquantel for the Treatment of Schistosomiasis ...

Tamirat Hailegebriel et al., Journal of Tropical Medicine

This systematic review and meta-analysis has indicated that praziquantel is still an appropriate drug for the treatment of human schistosomiasis in Ethiopia.

Soil-Transmitted Helminthiasis

Therapy and Prevention for Human Toxocariasis

Jean-François Magnaval, Emilie Bouhsira and Judith Fillaux, Microorganisms

To date, anthelmintic therapy for human toxocariasis remains rather unsatisfactory. There are few available compounds, and they are out of date. Their efficacy has rarely been assessed in prospective controlled trials. Clearly, anthelmintic treatment of the systemic forms of human toxocariasis should be standardized. A scoring system to quantify clinical severity should be developed by expert consensus so that therapeutic efficacy may be precisely assessed.

Prevalence of soil-transmitted helminth infections, schistosomiasis ...

John Paul Caesar Robles delos Trinos et al., PLOS Neglected Tropical Diseases

The burden of STH infections and schistosomiasis in children were significantly lower in studies conducted following the initiation of preventive chemotherapy. Eliminating morbidity and interrupting transmission, however, may require expanded control initiatives including community-wide treatment, and improved water, sanitation, and hygiene. Lymphatic filariasis burden has decreased since the implementation of preventive chemotherapy, with all but two provinces having reached the elimination of lymphatic filariasis as a public health problem.

Other

Bahia: Authorities recommend redoubled attention to outbreaks of mosquitoes ...

Andrea Hargraves, BRYTFMOnline

Public health specialist at Fundação Oswaldo Cruz (Fiocruz) in Brasilia, Claudio Mairowicz, highlights that 2020 has been a year for many cases, and therefore, one should not relax with lower infection rates in 2021.” Although there was no increase in One year to another, this is not a good comparison, because the previous year had large numbers,” he warns.

The elimination of human African trypanosomiasis: Achievements in relation ...

Jose R. Franco et al., PLOS Neglected Tropical Diseases

The steady progress towards the elimination of HAT is a testament to the power of multi-stakeholder commitment and coordination. At the end of 2020, the World Health Assembly endorsed a new road map for 2021–2030 that set new bold targets for neglected tropical diseases. While rhodesiense HAT remains among the diseases targeted for elimination as a public health problem, gambiense HAT is targeted for elimination of transmission. 

If neglected tropical diseases aren’t prioritised, achieving health equity ...

SCI Foundation

World NTD Day therefore provides a timely reminder for the global community to recognise its own role and responsibility in improving equity to ensure no one is left behind. 

Combatting neglected tropical diseases (NTDs) for a brighter future

Robin Schmid, IMA World Health

In honor of World NTD Day, IMA World Health is pausing to acknowledge the hard work and partnership that has helped to bring the global goals for controlling and eliminating neglected tropical diseases (NTDs) ever closer.

10 facts about the most dangerous diseases you've never heard of

Reuters, Times of India

On Saturday, charities will mark World Neglected Tropical Diseases Day, seeking to draw attention to a diverse group of communicable diseases that still cause immense suffering around the world, even though they can be prevented or cured.

Akwa Ibom raises the alarm over prevalence of tropical diseases

Ayoyinka Jegede, The Guardian

Akwa Ibom State Ministry of Health has raised the alarm over the prevalence of Neglected Tropical Diseases (NTD) in 11 councils of the state. Addressing newsmen in Uyo, yesterday, to commemorate World NTD Day, the Coordinator of Neglected Tropical Diseases in the state’s Ministry of Health and Public Relations Officer of Nigeria Medical Association (NMA), Dr. Aniekeme Uwa, said NTD had infected many in the state.

ASTMH: Call for Symposia for 2022 Annual Meeting

American Society of Tropical Medicine & Hygiene

Submit a symposium proposal for the 71st Annual Meeting, being held October 30 - November 3, 2022 at the Washington State Convention Center in Seattle, Washington. For those unable to attend in person, we will have a virtual option.

Last Call to Submit Research Proposals

Coalition for Operational Research on Neglected Tropical Diseases

These Requests for Proposals will close on January 31, 2022. 

- Increasing Effectiveness of Delivery of Preventive Chemotherapy against NTDs

-New diagnostics for schistosomiasis monitoring and evaluation

 

UPCOMING EVENTS

NOTE - Events may be postponed or cancelled due to the COVID-19 pandemic. Please check with event organizers to confirm events. 

World NTD Day 2022 
January 26, 2022
World Health Organization

100% Committed Launch Event
January 27, 2022
Uniting to Combat NTDs

Launch of the 2021 G-FINDER Neglected Disease Report
January 27, 2022
Policy Cures Research

World NTD Day
January 30, 2022

Are we doing enough to protect adolescent girls and women of reproductive age from the harm caused by worm infections ?
February 1, 2022
World Health Organization

Launch: WHO guideline on control and elimination of human schistosomiasis
February 15, 2022
World Health Organization

2022 Annual Meeting -Save the date
October 30-November 3, 2022
American Society of Tropical Medicine & Hygiene