'More Than Medicine: Nepal's Journey to Eliminate a Disease' and other NTD news

This news roundup is a collection of headlines and other items on neglected tropical diseases, and does not reflect the work or the views of the Coalition for Operational Research on Neglected Tropical Diseases or the Neglected Tropical Diseases Support Center.

Photo credit: Act to End NTDs | East

Lymphatic filariasis

More Than Medicine: Nepal's Journey to Eliminate a Disease

Act to End NTDs | East

It takes much more than medicine to eliminate neglected tropical diseases. In Nepal, the Ministry of Health is leading efforts to eliminate lymphatic filariasis (LF) and ensure that every person in the country is free from the impact of the disabling, mosquito-borne disease. Health workers are crucial to the success of Nepal's efforts. Follow along as Pushpa Devi Adhikari, a community health worker, takes the time to educate people in Baglung District, Nepal about the importance of taking medicine to prevent the spread of LF.

Mass drug administration campaign to eliminate Lymphatic Filariasis launched

Rhythma Kaul, Hindustan Times

The Union health ministry on Thursday launched a mass drug administration exercise in nine endemic states to reach its target of lymphatic filariasis elimination in the next four years.


Optimisation of the DNA dipstick as a rapid extraction method for Schistosoma japonicum in infected mice samples and spiked human clinical samples

Oyime P. Aula et al., Infectious Diseases of Poverty

Schistosomiasis remains a public health issue and the need for accurate and affordable diagnostics is crucial in the elimination of the disease. While molecular diagnostics are highly effective, they are expensive, with the main costs been associated with DNA extraction. The DNA dipstick is a rapid, affordable and simple purification method that allows DNA to be extracted from diagnostic samples within 30 s. We aimed to optimise the DNA dipstick method for samples from mice and egg-spiked human samples.

Two-stage automated diagnosis framework for urogenital schistosomiasis in microscopy images from low-resource settings

Prosper Oyibo et al., Journal of Medical Imaging

Automated diagnosis of urogenital schistosomiasis using digital microscopy images of urine slides is an essential step toward the elimination of schistosomiasis as a disease of public health concern in Sub-Saharan African countries. We create a robust image dataset of urine samples obtained from field settings and develop a two-stage diagnosis framework for urogenital schistosomiasis.


Modified Anterior Lamellar Recession for All Grades of Upper Eyelid Trachomatous Cicatricial Entropion

ENA Ibrahim et al., Clinical Opthalmology

This study aims to assess the combination of anterior lamellar recession (ALR) with blepharoplasty, suprasternal fixation, and internal eyelash bulb extirpation of aberrant lashes posteriorly located in patients with any grade of upper eyelid trachomatous cicatricial entropion.

This study showed the combination of ALR with blepharoplasty, suprasternal fixation, and cauterization or internal bulb extirpation of posteriorly located lashes procedure resulted in a high success rate in patients with any form of UCE with no increase in incidence or degree of lagophthalmos associated with UCE.


The Potential Impact of Climate Change on Infectious Disease

William Shadbolt, BioMed Central BugBitten

No matter who you are or where you are from, it’s almost inevitable that climate change will have a major impact on your life. Whether it be rising sea levels or changes in food production, it threatens to upend our lives and ecosystems. It can even affect which diseases you could be at risk for in your region.

This is because many vectors, especially cold-blooded ones, are better able to spread in warmer climates. Thus, as temperatures rise, it is likely that vectors such as mosquitos and ticks will be able to travel farther north and also be active for longer period of time during the year, which in turn means an increase in the number of vector-borne diseases, such as malaria and dengue fever, in both humans and animals. A study published in PLOS Neglected Tropical Diseases estimates that by 2050, the number of people at risk for diseases transmitted by two species of mosquitos, Aedes albopictus and A. aegypti, could increase by half a billion.

Non-target effects of chemical malaria vector control on other biological and mechanical infectious disease vectors

Ndey Bassin Jobe, Silvie Huijben, and Krijn P. Paaijmans, The Lancet Planetary Health

Public health insecticides play a crucial role in malaria control and elimination programmes. Many other arthropods, including mechanical and biological vectors of infectious diseases, have similar indoor feeding or resting behaviours, or both, as malaria mosquitoes, and could be exposed to the same insecticides. In this Personal View, we show that little is known about the insecticide susceptibility status and the extent of exposure to malaria interventions of other arthropod species. We highlight that there is an urgent need to better understand the selection pressure for insecticide resistance in those vectors, to ensure current and future active ingredients remain effective in targeting a broad range of arthropod species, allowing us to prevent and control future outbreaks of infectious diseases other than malaria.


Call for COR-NTD Research Links Sessions - 2023


The Secretariat of the Coalition for Operational Research on Neglected Tropical Diseases (COR-NTD) is pleased to announce the call for COR-NTD Research Links. This virtual series will include webinars, working meetings, research updates, etc., to share information about NTD operational research and related topics and will take place throughout the year.

Upcoming Events

NNN Conference 2023
September 19-21, 2023
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For All to Thrive: NTD Progress, Challenges, and Learning
September 22, 2023
USAID’s Act to End NTDs | East and Act to End NTDs | West programs

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October 16-17, 2023
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October 18-22, 2023

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November 1-2, 2023
Global Onchocerciasis Network for Elimination 

November 20-23, 2023
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