This news roundup is a collection of headlines and other items on neglected tropical diseases, and does not reflect the work or the views of the Coalition for Operational Research on Neglected Tropical Diseases or the Neglected Tropical Diseases Support Center.
Photo: A village resident in South Sudan’s Eastern Equatoria State uses a pipe filter to drink water safely. The device filters out tiny crustaceans that harbor Guinea worm larvae. Credit: The Carter Center
Carter Centre, an international non-governmental organisation has treated over 36 million Nigerians with Albendazole and Mectizan in line with efforts to prevent Lymphatic Filariasis (elephantiasis and hydrocele), a Neglected Tropical Disease (NTD) in Plateau and Nasarawa states. . . Eigege said the centre provided the treatments in almost a quarter of a century, adding that they also successfully carried over 10, 000 surgeries on patients with Lymphatic Filariasis (LF) that degenerated into hydrocele (enlarged testis) and lymphedema.
Preliminary results from a two-year study in six countries suggest significant improvement for people affected by lymphedema, thanks particularly to daily hygiene of the affected limbs.
As part of the ARISE project, which is funded by the Children’s Investment Fund Foundation, our teams have been applying new ‘Precision-mapping’ protocols to enhance efforts to combat the NTD, schistosomiasis. . . Working with governments in Uganda, Kenya, and Tanzania, through the use of precision mapping, ARISE is supporting Ministries of Health collect improved information on exactly which areas of the country still require treatment. The updated maps then guide the governments’ next steps around NTD control and focus treatment and prevention activities on areas most in need.
Addressing a silent and neglected scourge in sexual and reproductive health in Sub-Saharan Africa by development of training competencies to improve prevention, diagnosis, and treatment of female genital schistosomiasis (FGS) for health workers
Defining the skills necessary for FGS management is a critical step to prepare for proper diagnosis and treatment of women and girls in sub-Saharan Africa by trained health professionals. The suggested competencies can now serve as the foundation to create educative tools and curricula to better train health care workers on the prevention, diagnosis, and management of FGS.
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Parasitic Pathogens". Deadline for manuscript submissions: 20 November 2022.
Shifting the dynamics: implementation of locally driven, mixed-methods modelling to inform schistosomiasis control and elimination activities
The combination of participatory systems mapping and individual-based modelling was a rich strategy which explicitly integrated the perspectives of national and subnational policymakers and practitioners into the development of evidence. This strategy can serve as a method by which individuals who have not been traditionally included in modelling activities, and do not hold positions or work in traditional centres of power, may be heard and truly integrated into the development of evidence for decision-making in global health.
The aim of this policy brief is to promote the regular deworming of adolescent girls and women of reproductive age. Its target audience is decision-makers, programme managers and staff of nongovernmental organizations responsible for improving the health of women.
Johnson & Johnson Marks More Than 2 Billion Doses of Medicine Donated to Date to Help Combat Intestinal Worms
Millions of children in more than 50 countries have received deworming medication since the donation program began in 2006, enabling them to grow and thrive.
Speaking to Devex, Karutu discussed the importance of MDA and drug donations, the impact of COVID-19 on these initiatives, and what the future holds for tackling STHs and other NTDs.
Establishing a deworming programme for girls and women is difficult. However, targeting these groups through existing health-care services can substantially improve helminth-associated morbidity and newborn mortality. Ministries of health should promote the message that deworming is safe during pregnancy, and existing school-based deworming programmes should consider integrating women into their strategy.
In honour of World NTDs Day, on Jan. 30, Global Citizen spoke with Gladys Atto, an ophthalmologist working in Uganda’s rural communities, about her work supporting people with visual limitations caused by NTDs, fighting the stigma around these diseases, and taking action to eliminate them.
This will be our 23rd year of working to eliminate trachoma in Ethiopia. In collaboration with local partners, Orbis implements the WHO-recommended SAFE strategy (Surgery to correct trachomatous trichiasis; Antibiotics for the bacterium that causes trachoma; Facial cleanliness to reduce transmission; and Environmental improvement to reduce risk of transmission and infection).
Most recently, we administered nearly 9 million doses of trachoma-fighting antibiotics in just 1 month across 102 districts in Ethiopia’s Southern Nations, Nationalities, and People's Region (SNNPR), Sidama, and the new Southwest Region. Those doses are part of the over 12 million Orbis distributed in 2021.
Researchers from RTI International and the University of North Carolina Chapel Hill released a new application that uses machine learning technology to detect trachomatous trichiasis.
An observational assessment of the safety of mass drug administration for trachoma in Ethiopian children
There is a high level of adherence to the revised azithromycin dosing guidelines and low incidence of choking and ASEs.
Our country Nepal is endemic for eight NTDs which are lymphatic filariasis, trachoma, kala-azar, leprosy, soil-transmitted helminth infections, dengue, rabies, and cysticercosis. Snake bite venoming is an important NTD in Nepal whose morbidity and mortality burden in the country exceeds the collective burden of NTDs in Nepal. Nepal made a breakthrough progress in achieving the elimination of trachoma in 2018 and it is on track to eliminate Lymphatic Filariasis by 2026. Our country is progressively working toward the control and prevention of the NTDs.
On World NTD Day 2022, here are five innovations that can help bring the #BestScienceForAll. Mr Assani’s dream: New treatments for river blindness-Democratic Republic of Congo; Data for good: East African innovation-Kenya; Innovation in action: eliminating kala-azar in South Asia-India; Speeding up access: The iChagas app-Latin America; Accelerating scientific discovery: The Alphafold project-UK.
For World NTD Day on 30 January, Sightsavers is calling on the global community to work together to beat neglected tropical diseases. On the social media wall below, you can see why people worldwide are committed to the cause.
In 30 years of practice, Dr. Zerihun Tadesse has touched nearly every part of the Ethiopian health system. . . In recent years, Zerihun has developed a new appreciation for something he learned, not through his medical training, but as a boy from his mother: compassion. . . In the last quarter of 2020, Zerihun joined an eight-week program on “Compassionate Leadership and Resilience Training for Global Health Leaders” led by the Center for Compassionate Leadership and The Task Force’s Focus Area for Compassion and Ethics (FACE), with 22 participants from 11 countries.
World NTD Day 2022 and a new Kigali Declaration to galvanise commitment to end neglected tropical diseaseshttps://idpjournal.biomedcentral.com/articles/10.1186/s40249-021-00932-2
The initial NTD roadmap and the London Declaration on neglected tropical diseases have given a boost to implementation of NTD interventions allowing to come close to WHO’s 2020 targets. The launch of WHO’s second NTD roadmap 2021–2030 implored a new high-level political declaration to reiterate and invigorate commitments to end NTDs by 2030. As the Government of Rwanda has agreed to sponsor such a declaration, the Kigali Declaration on Neglected tropical diseases will be launched in 2022 and will be preceded by a global campaign to solicit an expanded group of stakeholders that are 100% Committed to ending NTDs to sign the declaration and announce their commitments.
Over the last 50 years, the work carried out by the international community has resulted in tremendous strides in making these debilitating conditions a thing of the past. . . Ending NTDs is not some utopian fantasy; it’s a tangible vision of the future that we can work toward every day. The World Health Organization (WHO) has outlined an ambitious roadmap to tackle these diseases by 2030, but carrying it out requires countries, partners, and Global Citizens to demonstrate strong political will. Here's why — and how — NTDs can become a thing of the past.
Lessons from the Ascend and ARISE programmes about what it takes to secure an enabling environment for government ownership include the following 4 key areas.
Since 2006, USAID has provided more than $1 billion to eliminate NTDs. Every $1 invested by the U.S. Government leverages $26 in donated medicines for mass treatment campaigns totaling $27.6 billion in value. Now nearly 500 million people no longer require treatment for three of the most burdensome NTDs.
The World Health Organization (WHO) has published a document that aims to support countries, international organizations, and partners to work together to identify common grounds to maximize efforts to control and eliminate neglected tropical diseases (NTDs). Ending the neglect to attain the sustainable development goals. One health: approach for action against neglected tropical diseases 2021-2030 – a companion document to the current NTD road map - provides guidance on One Health actions that are needed by stakeholders and how to support a paradigm shift towards One Health in national NTD programmes.
Neglected Tropical Diseases continue to affect 1.7 billion people around the world causing devastating effects. NTDs prevent children from going to school and adults from going to work, and they impair cognitive and physical development. The good news is that NTDs are preventable
Workshop summaries, key points and next steps from the 2021 meeting shared.
In a show of global solidarity, 100 landmarks in 32 countries – including Expo 2020 Dubai – will light up in unity on Sunday to mark the third annual World NTD (neglected tropical diseases) Day, a world movement aimed at galvanising the global health community and engaging the public to end NTDs.
Some of the global landmarks include Sheikh Zayed Bridge in Abu Dhabi, The Bell Tower in Perth, Australia; Tokyo Tower, Great Wall of China, Kuala Lumpur Tower, The Rome Colosseum, Jet d’ Eau, Niagara Falls, CN Tower, Carter Presidential Library, and Christ the Redeemer in Rio de Janeiro, Brazil.
Forgotten diseases: Achieving health equity to end the neglect of poverty-related diseases in Somalia
Of the 20 NTDs listed by WHO as endemic in tropical countries, the most prevalent in Somalia are: leprosy, schistosomiasis, soil-transmitted helminthiases and visceral leishmaniasis. In 2019, as Somalia was one of 16 countries reporting more than 1000 new cases of leprosy, the WHO Global Leprosy programme classified it as a global priority country. In August 2015, the Ministry of Health established an NTD section, after which the detection of new leprosy patients improved, and increased from 107 in 2015 to 2638 in 2021, despite a global drop in cases reported and detected in 2020 due to the spread of the coronavirus disease 2019 (COVID-19).
In this video from GlaxoSmithKline, we hear from people in Indonesia, Ghana, and Malawi about how neglected tropical diseases (NTDs) affect their lives. We learn about the problem and the solution from global health and NTD workers, including Dr. David Addiss, Honorable Khumbize Kandodo Chiponda, Dr. Jonathan King, Prof. Suma Krishnasastry, Dr. Sultani Matendechero, Dr. Katey Owen, Dr. Yao Sodahlon, Emily Wainwright, Emma Walmsley, and Tijana Williams.
Prioritizing the ‘neglected’: A peek into WHO South-East Asia Region’s efforts to end the NTD scourge
But soon countries began prioritizing resumption of essential health services along with pandemic response. Despite initial set back, preventive chemotherapy against NTDs reached 462 million people throughout the Region in 2020. Bangladesh implemented TAS, Timor-Leste pre-TAS/TAS and Indonesia introduced IDA in selected districts.
Preventive treatment of neglected tropical diseases (NTD) has saved many lives across Africa. However, obstacles persist as these diseases often affect impoverished communities in rural areas, conflict zones and hard-to-reach regions. These diseases are also almost absent from the global health agenda. Dr Paul Emerson, Director of the Atlanta-based International Trachoma Initiative, discusses ways to improve treatment and apply lessons for effective prevention and control.
Endemic in some of the poorest and most marginalized parts of the world, neglected tropical diseases prevent children from reaching their full potential. UNICEF is working with partners to keep children and communities safe and healthy.
Flour Mills of Nigeria Plc ( FMN), an integrated food and agro-allied group, has partnered with the END Fund to tackle prevalent neglected tropical diseases (NTDs) in eight locations across the country.
Neglected tropical diseases affect millions of people across Africa, yet the efforts to eliminate them and alleviate the suffering they cause receive little national attention. Professor Nicholas Midzi, an expert in preventive chemotherapy of neglected tropical diseases and the Director of Zimbabwe’s National Institute of Health Research, analyses factors contributing to low priority to these diseases and how to reverse the trend.
As the second country with the highest burden of Neglected Tropical Diseases (NTDs) in the world, over 120 million Nigerians are at the risk of one NTD or the other. . . Mamora added: “The target of the government is to eliminate all the preventable NTDs and ensure the effective control of case management NTDs on or before 2030. Mapping of the endemic areas with some of these diseases in all 774 LGAs in the country, putting in place policies and guidelines to guide all stakeholders etc…”
Тhе СОVІD-19 раndеmіс іntеrruрtеd іntеrvеntіоnѕ аnd еlіmіnаtіоn рrоgrаmѕ fоr thеѕе dіѕеаѕеѕ іn thе Аmеrісаѕ, ѕuсh аѕ mаѕѕ mеdісіnе аdmіnіѕtrаtіоn саmраіgnѕ, ѕurvеуѕ, аnd асtіvе саѕе trасіng. Тhеѕе wеrе mоѕtlу саnсеlеd іn 2020 аnd grаduаllу rеѕumеd іn 2021. РАНО wаrnѕ thаt thеѕе іntеrruрtіоnѕ mау dеlау thе еlіmіnаtіоn оr соntrоl оf ѕоmе оf thеѕе dіѕеаѕеѕ bеуоnd thе tіmеlіnеѕ рrороѕеd рrе-раndеmіс.
Vector-control measures like Indoor Residual Spraying rounds are undertaken in endemic areas to prevent sandfly breeding. . .
State and central governments have also introduced wage compensation schemes for those suffering from Kala-Azar and its sequela (a condition which is the consequence of a previous disease or injury) known as Post-Kala Azar Dermal Leishmaniasis.
COVID-19 led to the temporary halting of public health programmes in several countries. . . Innovations like using bowls to distribute medicines from a safe distance ensured COVID-appropriate behaviour on ground, even as dynamic dashboards highlighted areas of concern in real time and prompted improved planning and implementation. As a result, MDA coverage and compliance have improved and so far, 134 districts have stopped MDA after passing Transmission Assessment Survey (TAS).
COVID-19 related perception among some community members and frontline healthcare providers for NTD control in Ghana
COVID-19 has negatively affected the NTD programme. Education and the provision of personal protective equipment will be required to build the confidence of frontline care providers including community drug distributors and community members in order to enhance quality service and participation in future MDA activities.
An international partnership, which includes Rwanda Biomedical Center and University of Rwanda and led by the UK’s Brighton and Sussex Medical School, has been awarded over $9 million grant. From UK’s National Institute for Health Research, the grant will help to carry out vital work on some of the most ‘ignored’ diseases in Africa. The new grant will fund research in Rwanda, Ethiopia and Sudan working on three ‘neglected tropical diseases’: Podoconiosis, Mycetoma and scabies.
Just 14* human cases of Guinea worm disease occurred worldwide in 2021, drawing nearer to the goal of global eradication, The Carter Center announced Wednesday. It is the lowest annual case total ever recorded, and the cases occurred in just four countries. When The Carter Center assumed leadership of the global Guinea Worm Eradication Program in 1986, about 3.5 million human cases occurred annually in 21 countries in Africa and Asia.
Last year, Global Partnership for Zero Leprosy connected Vontade and other National Leprosy Programme supervisors across Mozambique with regional and international experts to share experiences. Together, these teams consulted health workers and people who have experienced leprosy to better understand patients’ experiences and find ways to improve health outcomes.
A key component of achieving control and elimination of neglected tropical diseases (NTDs) is effective supply chain management of preventive chemotherapy drugs for Mass Drug Administration (MDA) for trachoma, river blindness, lymphatic filariasis, soil-transmitted helminthiasis and schistosomiasis. This course explains the end-to-end process from planning and submitting donated drug requests through to waste management of expired and unserviceable stock and reverse logistics of unused tablets. It is essential knowledge for all levels of the health system that must work together to implement MDA. The course is free. Just register for an account on Open WHO and take the course!
The RGHI Fellowship Program 2022 is now open. The Reckitt Fellowship Program is designed to support early career researchers in the field of hygiene and health in the transition to becoming independent researchers. It is open to researchers with up to 5 years of experience post-PhD (exclusive of career breaks).
NOTE - Events may be postponed or cancelled due to the COVID-19 pandemic. Please check with event organizers to confirm events.
Launch: WHO guideline on control and elimination of human schistosomiasis
February 15, 2022
World Health Organization
2022 Annual Meeting -Save the date
October 30-November 3, 2022
American Society of Tropical Medicine & Hygiene