DOLF (Death to Onchocerciasis and Lymphatic Filariasis)
What is the frequency, type and severity of adverse events following triple-drug therapy (IVM+DEC+ALB, IDA) compared to the standard two-drug treatment (DEC+ALB, DA) in infected and uninfected individuals in a community?
What is the frequency, type and severity of adverse events following triple-drug therapy (IVM+DEC+ALB, IDA) compared to the standard two-drug treatment (DEC+ALB, DA) in infected and uninfected individuals in a community?
What is the frequency, type and severity of adverse events following triple-drug therapy (IVM+DEC+ALB, IDA) compared to the standard two-drug treatment (DEC+ALB, DA) in infected and uninfected individuals in a community?
Assess the overall acceptability of the 3-drug treatment in the community as compared to the 2-drug treatment
Assess the overall acceptability of the 3-drug treatment in the community as compared to the 2-drug treatment
Analysis of MDA frequency and Brugia in Indonesia
Comparison of 2X vs. 1X per year MDA on Brugia with MDA of DEC/Alb , plus STH evaluation
Comparison of safety profile and acceptability between triple drug therapy (IVM,DEC,ALB) and standard two-drug therapy (DEC, ALB), plus STH evaluation.
Analysis of MDA frequency in Indonesia and Papua New Guinea
Comparison of 2X vs. 1X per year MDA, W. bancrofti with MDA of DEC/Alb, plus STH evaluation
Analysis of MDA frequency in Liberia and Cote D'Ivoire
Comparison of 2X vs. 1X per year MDA on W. bancrofti with MDA of IVM/Alb, plus STH evaluation (and Schistosoma in Foya only)
Analysis of MDA for LF in loa endemic countries
Community MDA with 2X Alb alone for W. bancrofti in areas co-endemic for L. loa, plus STH evaluation
Comparison of Filariasis Binax Test and Alere Test Strip
Binax Now Filariasis Test vs. Alere Filariasis Test Strip Comparison
Randomized trial of triple therapy (DEC/Alb/Iver) in Papua New Guinea
Randomized Clinical Trial comparing triple triple therapy of DEC/Alb/Iver vs. DEC/Alb alone
Randomized trial of albendazole alone for LF in Cote d'Ivoire
Randomized Clinical Trial of Albendazole vs Ivermectin+Albendazole for lymphatic filariasis treatment and elimination.
Randomized trial of Ivermectin/Albendazole vs. Ivermectin alone
Randomized clinical trail comparing treatment with Albendazole and Ivermectin to Ivermectin alone for Onchocerciasis.