International Center for Excellence in Research (ICER-Mali)
Doxycycline for Clinical Management of Filarial Lymphedema (Mali)
Determine whether doxycycline treatment daily for 6 weeks improves clinical outcomes (swelling, acute attacks) in lymphedema patients.
A qualitative exploration to understand the barriers and facilitators related to never treatment during mass drug administration among the migrant and mobile populations in Mali
Primary Research Question: To explore the reasons behind never treatment during PC-NTDs MDA in Mali and provide evidence to support the development of an effective programmatic response, including a further quantitative assessment of the factors associated with never treatment and recommendations for qualitative assessments of never treatment.
Secondary Research Question:
The NTD program in Mali has been highly affected by growing conflict and regional instability over the past five years. Earlier research supported by COR-NTD (200D Mali) indicated that 12% of nomads and other mobile populations were never treated during MDA with more than 35% of the participants stating that they did not participate in the last MDA campaign. The study team proposes conducting 12 focus groups and 24 in-depth interviews with a variety of mobile populations and health care workers in two health districts of Mali: Tominian and Kalaban-coro. The mobile populations are divided into three categories: economic migrants, internally displaced persons, and nomads. Following this formative research, the study team aims to draft and pilot a standardized, closed-ended question on reasons for NT for inclusion in programmatic questionnaires and surveys. They also aim to use this research as a springboard to develop a rapid qualitative assessment for never treatment in mobile populations.
Monitoring after stopping mass treatment of Lymphatic Filariasis with ivermectin and albendazole in Mali border health districts with Guinea, Côte d'Ivoire, Burkina Faso, among migrants, gold panning sites, refugees, and internally displaced persons.
What is the status of lymphatic filariasis transmission eight (8) years after the cessation of mass drug administration in border areas, gold panning sites, among refugees and internally displaced persons of the country?
Could the multiplicity of gold panning sites and the security context marked by a strong movement of people have an impact on the re-emergence of lymphatic filariasis infection?