University of Ibadan
Developing an RDT for schistosomiasis haematobium using Schistosoma antigens present in the urine
1. Can we identify and characterize protein-based biomarkers for schistosomiasis and schistosomiasis induced bladder pathologies using urine samples?
2. Can we identify urine antibodies to, or antigens of, S. bovis and determine their utility for diagnosis and risk of schistosomiasis haematobium and schistosomiasis-associated bladder pathologies?
3. Can we validate the identified biomarkers for consistency and reliability and inclusion in an RDT?
Factors influencing uptake and delivery of preventive chemotherapy for helminthic neglected tropical diseases among selected hard-to-reach communities in Abia, South-Eastern Nigeria
1. What cultural and household factors influence the uptake of PC among people living in selected communities?
2. How do the communities perceive or feel about the interventions they receive?
3. What are the barriers impeding the implementation of preventive chemotherapy for helminthic-NTDs in the study area?
4. What other health-service related factors affect the delivery of preventive chemotherapy intervention for helminthic-NTDs?
Environmental DNA (eDNA) as a tool for detecting schistosome snail hosts in Nigeria and possible impacts of environmental factors
1. Can snail eDNA be used to detect and monitor schistosome snail hosts in freshwater environments in Nigeria?
2. How do prevailing environmental factors affect sensitivity of this snail eDNA method for schistosomiasis monitoring?