Laboratory analysis of Ov16 ELISA and Skin snip PCR to support surveillance activities in National programs. Multi-country comparison of diagnostic tools to detect Onchocerca volvulus

Laboratory analysis of Ov16 ELISA and Skin snip PCR to support surveillance activities in National programs. Multi-country comparison of diagnostic tools to detect Onchocerca volvulus

Review status: 
Accepted

Research question

To compare the performance of the diagnostic tools currently available for O. volvulus in terms of their relative sensitivity, species-specificity and practical use by countries.  Comparison of the utility of these tools for mapping and surveillance in settings with different levels of endemicity for onchocerciasis (Oncho), lymphatic filariasis (LF) and/or loiasis.

Study sites

Notes

Total sample size 2200